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● Properties and Chemical Characteristics
● Common Uses and Applications
>> Pharmaceutical and Topical Products
>> Cosmetics and Personal Care
>> Research, Veterinary, and Industrial Uses
● Why Choose Reputable Suppliers?
● Top Places to Buy Benzocaine Powder Worldwide
>> Leading Chinese Manufacturers and OEM Factories
● OEM and ODM Services for Global Brands
● Step-by-Step Guide to Purchasing Benzocaine Powder
● Quality Assurance and Testing Protocols
● Pricing, Logistics, and Economics
● Safety, Regulatory, and Storage Guidelines
● Alternatives and Market Trends
● FAQ
>> 1. What is the typical purity level for pharmaceutical-grade benzocaine powder?
>> 2. What are the minimum order quantities for bulk purchases?
>> 3. How long does international shipping take from China?
>> 4. Can suppliers provide private labeling and custom formulations?
>> 5. Is benzocaine powder legal for import into Western countries?
Finding reliable sources for high-purity benzocaine powder is essential for businesses in biotechnology, pharmaceuticals, medical devices, and related fields, especially for those seeking OEM services from trusted Chinese factories. This comprehensive guide details everything you need to know about sourcing benzocaine powder, from its properties and applications to top suppliers, buying processes, quality checks, and customized production options tailored for international brands, wholesalers, and manufacturers.
Benzocaine powder is a widely used local anesthetic belonging to the ester-type class, chemically known as ethyl 4-aminobenzoate with CAS number 94-09-7 and molecular formula C9H11NO2. It appears as a fine, white crystalline powder that is sparingly soluble in water but highly soluble in ethanol, chloroform, and ether. This compound works by blocking voltage-gated sodium channels in nerve membranes, preventing the initiation and conduction of nerve impulses, which results in localized numbness without significant systemic absorption when applied topically.
Pharmaceutical-grade benzocaine typically boasts a purity of 99% or higher, verified through high-performance liquid chromatography (HPLC) and other analytical methods. Its melting point ranges from 128-132°C, making it stable under normal storage conditions. Beyond medical uses, benzocaine serves as a key ingredient in various formulations, prized for its rapid onset of action—often within 1-5 minutes—and duration of 10-30 minutes, depending on concentration and vehicle.
In industrial settings, benzocaine powder is synthesized through esterification of p-aminobenzoic acid with ethanol, followed by purification steps to remove impurities. Chinese manufacturers have perfected this process at scale, producing metric tons annually while adhering to Good Manufacturing Practices (GMP). This scalability allows for competitive pricing and consistent quality, crucial for OEM partners developing branded products.
Benzocaine's low water solubility (approximately 0.4 g/L at 20°C) makes it ideal for oil-based ointments and sprays, where it provides prolonged release compared to more soluble anesthetics like lidocaine. It exhibits low toxicity with an LD50 greater than 10 g/kg in rats, though overuse can lead to methemoglobinemia, a rare blood disorder prompting warnings for pediatric applications. Stability testing shows it remains potent for 2-3 years when stored in airtight containers away from light, heat, and moisture.
Key specifications for buyers include assay content (>99%), loss on drying (<0.5%), heavy metals (<10 ppm), and residue on ignition (<0.1%). Reputable suppliers provide detailed Certificates of Analysis (COA) and Safety Data Sheets (SDS) for each batch, ensuring compliance with pharmacopeial standards like USP, EP, or BP. For biotech firms, understanding these properties aids in formulation design, such as creating microemulsions for enhanced bioavailability or combining with penetration enhancers for transdermal delivery.
Benzocaine shines in over-the-counter (OTC) remedies for minor skin irritations, including sunburn relief creams, insect bite gels, and hemorrhoidal ointments at concentrations of 5-20%. Factories blend it into stable emulsions, adding humectants like glycerin or preservatives for shelf life exceeding 24 months. For oral care, 10-20% benzocaine lozenges or sprays soothe sore throats and canker sores, popular in markets like the UK and US.
Dentists rely on benzocaine gels (20%) for pulpal anesthesia before injections or root planing. Medical device manufacturers incorporate it into impression materials or retraction cords, providing patient comfort during procedures. OEM services allow customization, such as flavored gels for pediatric dentistry or alcohol-free versions for sensitive mucosa.
In lip plumpers, aftershaves, and cold sore treatments, benzocaine (1-5%) delivers a tingling numbness that consumers associate with efficacy. Bulk powder enables private-label runs for beauty brands, with factories offering micronization for smoother textures or encapsulation to mask taste.
Laboratories purchase benzocaine for electrophysiology studies on ion channels or as a model compound in drug metabolism assays. Veterinarians use it in animal husbandry for wound dressings. Industrially, it's a precursor in polymer synthesis or quality control standards. Small 100g-1kg packs cater to R&D, while 25kg drums suit production.
Expanding into biotech innovations, benzocaine derivatives are explored in nanoparticle drug delivery systems for targeted anesthesia, reducing dosage needs. Chinese OEM factories support these by providing R&D-scale synthesis and scale-up expertise.
Sourcing from unverified vendors risks adulterated powder with fillers like talc or under-pure product causing inefficacy or allergic reactions. Reputable suppliers mitigate this through third-party testing (e.g., SGS, Eurofins), batch traceability, and regulatory filings like Drug Master Files (DMF). Chinese factories lead globally, producing 70-80% of the world's benzocaine due to raw material access and cost efficiencies—often 30-50% cheaper than US or EU alternatives.
Key evaluation criteria include:
- Certifications: GMP, ISO 9001, FDA-inspected facilities.
- Experience: 10+ years in API export, serving Fortune 500 pharma clients.
- Customization: OEM/ODM capabilities for formulas, packaging, and branding.
- Support: Technical data sheets, stability studies, and post-sale assistance.
For international brands, partnering with factories like those behind supplybenzocaine.co.uk ensures seamless integration into supply chains, with options for Halal/Kosher certifications or vegan-compliant processes.
China dominates with vertically integrated factories offering end-to-end services. supplybenzocaine.co.uk represents premier OEM providers specializing in biotech and pharma raw materials, delivering ≥99% pure powder at $24-125/kg. These facilities handle everything from synthesis to filling aerosol cans under your label, with MOQs as low as 1kg for samples.
Other notables include Haoze Bio for wholesale and custom synthesis, producing under cGMP with export volumes exceeding 100 tons yearly. They excel in blending benzocaine with actives like menthol for synergistic effects.
UK-based Qlab.uk offers lab-grade benzocaine compliant with REACH regulations, ideal for small EU orders (100g+). Delivery within 1-3 days suits urgent needs, though pricing ($100-300/kg) reflects import costs.
Carolina Chemical provides USP-grade powder in 100g-5kg packs with US warehousing for quick shipping. Sigma-Aldrich distributes via lab networks, focusing on research quantities.
Pharmaoffer.com connects buyers to verified API makers, filtering by GMP status and location. These platforms facilitate RFQs for competitive bidding.
| Supplier Type | Price Range (per kg) | Minimum Order | OEM/ODM | Key Strengths |
|---|---|---|---|---|
| Chinese OEM Factories (e.g., supplybenzocaine.co.uk) | $24-125 | 1kg | Full Service | Cost, Scale, Customization |
| UK/EU Labs (e.g., Qlab.uk) | $100-300 | 100g | Limited | Fast Local Delivery |
| US Distributors (e.g., Carolina Chemical) | $125-450 | 100g | No | Quality Assurance |
| B2B Platforms (e.g., Pharmaoffer) | Varies | 1kg | Varies | Global Network |
For wholesalers and producers, OEM factories transform bulk powder into finished goods. The process begins with your brief—e.g., 15% benzocaine spray with eucalyptus scent—followed by prototype development (2-4 weeks), stability testing per ICH guidelines, and pilot runs. Full production scales to 10,000+ units, with options for silk-screen printing, shrink sleeves, or multi-language labels.
Benefits include 40% cost savings, faster time-to-market (3-6 months), and IP protection via NDAs. Chinese providers like those at supplybenzocaine.co.uk support regulatory submissions, such as FDA 510(k) for devices or cosmetic notifications.
Real-world example: A European brand outsourced 10,000 units of numbing gel, achieving 2x profit margins through optimized formulations.
1. Define Requirements: Specify purity, quantity, end-use, and regulatory needs (e.g., USP for pharma).
2. Shortlist Suppliers: Use platforms or directories; request COAs from 3-5.
3. Request Samples: Order 100g-1kg ($50-200) for in-house testing (HPLC, IR spectroscopy).
4. Verify Quality: Check melting point, solubility, microbial limits.
5. Negotiate Terms: Secure DDP shipping, payment via LC/TT, and volume discounts.
6. Place Order: Start with trial batch; scale up post-validation.
7. Monitor Delivery: Track via FedEx/DHL; inspect upon arrival.
Common pitfalls: Skipping samples or ignoring storage advice (cool, dry, <25°C).
Insist on COA detailing identity (IR/NMR), purity (HPLC >99.5%), impurities (<0.1%), and contaminants (endotoxins <0.5 EU/mg). Factories conduct in-process controls like pH monitoring and yield optimization. Post-production, accelerated stability tests simulate 2-year shelf life.
For OEM, suppliers perform microbial challenge tests and compatibility studies with your packaging.
Pricing tiers:
- 1kg: $125
- 5-25kg: $90-34
- 100kg+: $24-50
Logistics: 3-7 days air to UK/US/EU; sea for >100kg. Duties average 0-5% for APIs.
Economic edge: Chinese production leverages low energy costs and subsidies, passing savings to OEM clients.
Handle with gloves, goggles; avoid dust inhalation (TLV 10 mg/m³). Store at 15-30°C in HDPE drums or foil bags. Regulatory status: Non-controlled, but pharma imports require end-user declarations.
Lidocaine or pramoxine offer alternatives; benzocaine excels in non-water-soluble apps. 2026 trends: Biodegradable patches and AI-optimized formulations from Chinese R&D hubs.
Sourcing benzocaine powder from established Chinese OEM factories like supplybenzocaine.co.uk guarantees superior quality, unbeatable pricing, and tailored solutions for your biotech, pharma, or medical device ventures. Don't settle for less—contact our expert team today for free samples, personalized quotes, or full-scale OEM partnerships. Elevate your product line with reliable, high-purity supplies. Email [email protected] or visit supplybenzocaine.co.uk to get started now! Contact us to get more information!
Pharmaceutical-grade benzocaine powder should be ≥99% pure, confirmed via HPLC analysis, with full COA documentation to ensure compliance with USP/EP standards.
Minimum orders start at 1kg for samples, scaling to 10-50kg for OEM production runs, allowing flexibility for startups and large wholesalers alike.
Delivery typically takes 3-7 days via DHL or FedEx to the UK, US, or EU, with full tracking and DDP options to simplify customs.
Yes, full OEM/ODM services include custom formulas, branding, packaging design, and regulatory support for seamless market entry.
Yes, it's legal for licensed commercial use in pharma, cosmetics, and research; always verify local regulations and provide end-user statements.
1. https://carolinachemical.com/product/benzocaine-powder/
2. https://www.supplybenzocaine.co.uk/where-to-buy-benzocaine-powder.html
3. https://www.sigmaaldrich.com/US/en/search/where-to-buy-benzocaine-powder?focus=documents&page=1&perpage=30&sort=relevance&term=w...
4. https://pharmaoffer.com/api-excipient-supplier/local-anesthetics/benzocaine/china
5. https://www.cristalchem.com/2025/11/01/where-to-buy-benzocaine-powder/
6. https://www.supplybenzocaine.co.uk/where-to-buy-benzocaine-powder-uk.html
7. https://shopbvv.com/products/benzocaine-powder
8. https://www.haozepharm.com/human-pharma-raw-materials/others/raw-benzocaine-powder.html
9. https://qlab.uk/product/benzocaine-powder/
10. https://pharmaoffer.com/zh-CN/api-excipient-supplier/local-anesthetics/benzocaine
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