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● What Is Penicillin G Procaine?
>> Clinical Uses of Penicillin G Procaine
● Pricing Factors of Penicillin G Procaine
● Manufacturing and Sourcing From China
● Safety Profile and Precautions
● Frequently Asked Questions (FAQ)
>> 1. What is Penicillin G Procaine used for?
>> 2. How much does Penicillin G Procaine cost?
>> 3. Is Penicillin G Procaine available for OEM?
>> 4. What are the main safety concerns with Penicillin G Procaine?
>> 5. How is Penicillin G Procaine administered?
Penicillin G Procaine is a vital antibiotic used extensively in both human and veterinary medicine for the treatment of bacterial infections. It combines penicillin G, a powerful bactericidal antibiotic, with procaine, an anesthetic that reduces injection pain, making it especially preferred for deep intramuscular injections. For overseas brands, wholesalers, and manufacturers sourcing from China, an understanding of the pricing dynamics, clinical applications, manufacturing processes, and OEM availability of Penicillin G Procaine is paramount in making informed purchasing decisions.
This article offers an in-depth exploration of Penicillin G Procaine, emphasizing its uses, price determinants, administration, safety profiles, and opportunities for OEM partnerships with Chinese pharmaceutical manufacturers. The guide also includes embedded images and video placeholders to enhance comprehension, culminating with a conclusion urging interested clients to reach out, and a frequently asked questions section addressing common queries.
Penicillin G Procaine is a combination drug consisting of penicillin G, a beta-lactam antibiotic that acts by disrupting bacterial cell wall synthesis, resulting in bacterial death, and procaine, a local anesthetic that mitigates injection pain. This formulation offers a prolonged antibacterial effect by slowly releasing penicillin into the bloodstream from the site of injection.
Penicillin G Procaine is prescribed for infections caused by penicillin-sensitive bacteria, including:
- Respiratory tract infections caused by pneumococci
- Streptococcal infections such as tonsillitis, scarlet fever, and erysipelas
- Skin and soft tissue infections
- Syphilis at various stages
- Anthrax
- Veterinary applications for infections in cattle, horses, pigs, and sheep
Its use is favored where sustained antibiotic blood levels are required over an extended period, especially following intramuscular administration.
The cost of Penicillin G Procaine is affected by multiple factors:
- Pharmaceutical Grade and Purity: High purity (above 98%) and GMP-certified batches typically command higher prices due to stringent quality controls.
- Formulation and Packaging: Costs vary depending on whether the product is supplied as bulk active pharmaceutical ingredient (API) or fully formulated injectable suspensions. Vial sizes and packaging materials also influence prices.
- Regulatory Compliance: Manufacturers adhering to international quality standards like ISO 9001, GMP certification, and regulatory dossiers like USDMF (United States) or CEP (European) can price their products at a premium.
- Order Volume and OEM Partnerships: Larger quantities often benefit from volume discounts. Long-term OEM collaborations tend to offer better negotiated prices.
- Market and Supply Chain Variables: Raw material costs, geopolitical dynamics, and transportation logistics, particularly impacting China-based suppliers, modify price fluctuations.
Typical Price Ranges:
- Penicillin G Procaine Injection (100ml vial): Approximately $17 to $50 USD per vial
- Bulk API (per gram): Between $1 and $5 USD depending on purity
- Finished Dosage Forms (varied strengths and packaging): Typically $35 to over $200 USD per unit
These figures give a general scope; actual prices are subject to supplier negotiation, product specifications, and certification status.
China is among the largest producers and exporters of Penicillin G Procaine, offering reliable access to raw materials and finished products through numerous pharmaceutical companies. Leading manufacturers include entities such as Hebei Huizhong Medicine, Shijiazhuang Shimu Pharmaceutical, and Hebei Veyong Pharmaceutical, all known for their GMP compliance and international supply experience.
Chinese suppliers provide full OEM services, including customized packaging and regulatory documentation, to cater to foreign pharmaceutical brand requirements. This affords flexibility and cost-effectiveness to global buyers seeking to private-label or white-label Penicillin G Procaine products.
Penicillin G Procaine is administered strictly by deep intramuscular injection. Common administration sites include the upper outer quadrant of the buttocks or the midlateral thigh in children. Careful technique is necessary to avoid nerve or artery injury, which can cause severe neurologic damage.
- Adults and children over 60 pounds: Generally 600,000 to 1,000,000 units daily
- Pediatric patients under 60 pounds: Around 300,000 units daily
- Duration for mild to moderate infections: Typically 10 days minimum treatment
- Severe infections: Dosage adjusted as needed under medical supervision
The procaine component provides a slow dissolution rate, sustaining penicillin levels in the bloodstream for about 15 to 20 hours after injection, reducing injection frequency compared to aqueous penicillin G.
Penicillin G Procaine is generally safe when properly administered, but precautions are essential due to potential adverse effects:
- Allergic Reactions: Ranging from mild rashes to life-threatening anaphylaxis, especially in patients allergic to penicillin-class antibiotics.
- Injection Site Reactions: Local pain, inflammation, or abscess formation at injection sites.
- Neurologic Effects: Improper injection technique near nerves can cause pain, numbness, or nerve damage.
- Contraindications: Not recommended for patients with penicillin hypersensitivity or severe renal impairment without dose adjustment.
It is critical for healthcare providers to evaluate patient history thoroughly and monitor for adverse reactions, especially during initial dosing.
Our factory specializes in offering bespoke OEM manufacturing of Penicillin G Procaine products designed to satisfy international brand and regulatory expectations. Clients enjoy:
- Flexible formulation and packaging solutions tailored to customer branding needs
- Access to certified production facilities that ensure product quality and compliance
- Full regulatory support, including documentation and batch release testing
- Competitive pricing for bulk and ongoing production contracts
- Reliable lead times and global logistics for seamless supply chain integration
Such comprehensive OEM capability empowers pharmaceutical brands, distributors, and wholesalers to expand product lines with quality assurance and cost efficiency.
Penicillin G Procaine is an essential pharmaceutical agent in both human and veterinary medicine due to its effective antibacterial action combined with local anesthetic properties mitigating injection discomfort. Pricing is influenced by quality standards, packaging, regulatory compliance, and order size, while China remains a key global manufacturing hub offering competitive OEM sourcing options. Brands and wholesalers seeking dependable Penicillin G Procaine vendors can leverage proven Chinese manufacturing partnerships for optimal quality, cost, and customization.
For more information and tailored quotations on Penicillin G Procaine OEM opportunities, contact us today to discuss your requirements and secure your pharmaceutical supply chain with a reputable manufacturer.
Penicillin G Procaine treats a variety of bacterial infections, including respiratory tract infections, streptococcal diseases, skin infections, syphilis, and anthrax. It is chosen for its sustained antibiotic effect following intramuscular injection.
Prices typically range from about $17 to $50 per 100ml vial for injectable suspensions. Bulk API costs can be between $1 and $5 per gram. Actual prices depend on product purity, certification, packaging, and order volume.
Yes, many Chinese manufacturers support OEM services, offering custom packaging, labeling, and regulatory documentation tailored to international clients.
The major risks include allergic reactions, injection site pain or irritation, and potential nerve damage if improperly injected. The medication is contraindicated for patients allergic to penicillin.
It is administered as a deep intramuscular injection, typically into the buttock or thigh, to ensure slow release of penicillin and prolonged antibacterial activity.
[1](https://www.drugs.com/dosage/penicillin-g-procaine.html)
[2](https://www.rxlist.com/penicillin-g-procaine-drug.htm)
[3](https://www.drugs.com/pro/penicillin-g-procaine.html)
[4](https://labeling.pfizer.com/showlabeling.aspx?id=718)
[5](https://www.fda.gov/drugs/bioterrorism-and-drug-preparedness/questions-and-answers-consumers-penicillin-g-procaine)
[6](https://www.mayoclinic.org/drugs-supplements/penicillin-g-benzathine-and-penicillin-g-procaine-intramuscular-route/description/drg-20452194)
[7](https://reference.medscape.com/drug/penicillin-g-procaine-999572)
[8](http://inspection.canada.ca/en/animal-health/livestock-feeds/medicating-ingredients/penicillin)
[9](https://www.veteranshealthlibrary.va.gov/MedicationsVA/203,a615052)
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